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Nexium, Prilosec and Prevacid, commonly used to treat heartburn, indigestion, gastritis and/or acid reflux, have recently been linked to kidney disease and complications in two major independent medical studies. In one January 2016 medical study by the Journal of American Medical Association involving more than 250,000 patients, it was reported that there is a significant increased risk to patients taking proton pump inhibitors of developing acute kidney failure and chronic kidney disease.

Accordingly to CBSNEWS article: Common Heartburn Drugs Linked With Kidney Disease

People who use proton pump inhibitors (PPIs) have a 20% to 50% higher risk of chronic kidney disease compared with nonusers, said lead author Dr. Morgan Grams, an assistant professor of epidemiology at Johns Hopkins University in Baltimore.

Newer studies now show a link between the drugs and chronic kidney disease, in which the kidneys lose their ability to filter blood effectively.

Over time, chronic kidney disease can lead to kidney failure, forcing someone to undergo regular dialysis and possibly a kidney transplant, according to the U.S. National Institutes of Health.

Nexium, also known as the “purple pill” has been widely used by millions of consumers since its release by AstraZeneca in 2001. Given its vast consumption, this is alarming news for those that ingest the drug on a daily basis.

Although it has been used by millions of people and is widely thought to be safe, several studies suggest that side effects of Nexium and other proton pump inhibitors (PPI) Prilosec and Prevacid may increase the risk of serious kidney problems, which were not adequately disclosed by the drug makers, including:

Acute Kidney Injury

Kidney Failure

Acute Interstitial Nephritis

Chronic Kidney Disease

Kidney Transplant Surgery

The Dangerous Drug and Device Attorneys at Childers, Schlueter & Smith are now reviewing kidney injury claims related to Nexium, Prilosec and Prevacid. If you or a loved one have been diagnosed with Chronic Kidney Disease, Acute Kidney Injury, Renal or Kidney Failure, or other kidney related issues, while taking a proton pump inhibitor like Nexium, Prilosec or Prevacid, please call us immediately for a free initial consultation. All inquiries are kept completely confidential: 1-800-641-0098


  1. Gravatar for Linda Corey
    Linda Corey

    I have chronic kidney disease and have taken Prilosec for years for acid reflux and chronic gastritis. My doctor took me off aspirin, ibuprofen and naproxen, but I think Prilosec is the real culprit.

  2. Gravatar for Eileen

    What about Tecta. l a day for 12 mths.?

  3. Gravatar for Mark Duff
    Mark Duff

    I am a 6-year survivor of pancreatic cancer and I am looking for advice. I have been off of Nexium, Prilosec and all other Proton pump inhibitors for about 1 year. Although I am not aware of any kidney problems at this time do you think it would be in my best interest if I was to have a checkup with my primary care physician.

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